National Cancer Institute, Research Contracts Branch, PSAS, 6120 Executive Blvd, EPS/Room 638, Bethesda, MD 20892-7227

B -- COLORECTAL CANCER SCREENING BEHAVIORS AMONG ALASKA NATIVES SOL NCI-RFQ-90232-NV DUE 092399 POC Debbie Moore, Purchasing Agent (301) 402-4509, Todd Cole, Contracting Officer (301) 402-4509 The National Cancer Institute (NCI), Division of Cancer Control and Population Sciences plans on procuring analyses of screenings for colorectal cancer among Alaskan Natives from the Southcentral Foundation, 4501 Diplomacy Drive, Suite 200, Anchorage, Alaska 99508. Alaskan Natives have the highest incidence of colorectal cancer of all racial and ethnic groups in the United States. The incidence and mortality rates exceed those for other populations and all other Indian Health Service areas. Forty-one percent of all Alaskans, including 18 percent of Alaskan Natives, live in Anchorage, the largest city. Forty-six percent of Alaskan Natives live in rural areas with less than 1,000 persons. To understand the current screening practices within the health care systems serving Alaskan Natives, investigators need to abstract the medical records of 500 natives from an urban site (Anchorage) and 500 natives from a rural site in the Yukon-Kuskokwim Delta region. The objectives of this analysis/study are: 1) to document the screening recommendations of health care providers; 2) to identify the screening procedures performed; 3) to compare rural and urban screening practices; 4) to compare screening practices of patients at greater risk due to a history of polyps; 5) to analyze screening rates and build a database that will support a screening program; and 6) to make recommendations for implementation of a statewide colorectal cancer screening program. The Contractor shall identify a sample of 1,000 subjects greater than 50 years of age who have had at least two visits to a health care provider at the Yukon-Kuskowim Health Corporation in Bethel or at the Alaska Native Medical Center in Anchorage over a four-year period 1994 through 1998. From each site, 450 patients will be randomly selected. An additional random sample of 50 patients from each site with a history of polyps will be selected. The contractor shall abstract the patient records for data on fecal occult blood tests, digital rectal exams, sigmoidoscopy or colonoscopy, barium enema, and record of provider's screening recommendation. The contractor shall analyze the collected data comparing screening rates and statistics with comparisons to national and statewide rates. All information will be held confidentiality and all clearances shall be obtained. Southcentral Foundation is the provider of health care services for the urban target population and has an agreement with organizations, such as the Yukon-Kuskowim Health Corporation, providing care to the rural populations. This is the only organization that has coverage of the populations and access to enough records to complete the aforementioned study. Furthermore, the Foundation has the requisite health care experts that are needed to perform such a study. Southcentral Foundation is the only source known to the NCI Researcher that can perform the above study by virtue of having access to such a broad population of Alaskan Natives. This notice of intent is not a request for competitive quotation. However, if any interested party believes it can meet the above requirement, it may submit a statement of capabilities. The capability statement and any other furnished information must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can fully meet the requirements. Capability statements must be received in theDebbie Moore, Purchasing Agent on (301)402-4509. A determination by the Government not to compete this proposed requirement based on responses to this notice is solely contracting office by 2:00 p.m., EST on September 23, 1999. If you have any questions, please contact within the discretion of the Government. Information received shall be considered solely for the purpose of determining whether to conduct a competitive procurement. No collect calls will be accepted. Posted 09/07/99 (W-SN376834). (0250)

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