National Institutes of Health, National Institute of Allergy and Infectious Diseases, Contract Management Branch, Room 2230, 6700-B Rockledge Drive, MSC 7612, Bethesda, MD 20892-7612

A -- SAFETY EVALUATION FOR ANTI-INFECTIVE THERAPIES SOL NIH-NIAID-DAIDS-00-29 DUE 123099 POC Ross Kelley, Contract Specialist, (301) 402-2234 The Drug Development and Clinical Sciences Branch, Therapeutics Research Program, Division of AIDS, National Institute of Allergy and Infectious Diseases (NIAID), NIH, has a requirement to provide preclinical safety and pharmacokinetic assessments of experimental anti-infective therapies. This effort will support a comprehensive portfolio of contract resources to discover and develop novel therapeutic agents for the prevention and treatment of infections caused by human immunodeficiency virus, AIDS-associated opportunistic pathogens, and other infectious agents. This contract will help assure that experimental therapies will be comprehensively evaluated for safety prior to administration to humans, using protocols that are conducted in compliance with FDA's current Good Laboratory Practices regulations. It is anticipated that one (1) cost reimbursement, completion type contract will be awarded for a period of seven (7)years, beginning approximately July 1, 2000. RFP-NIH-NIAID-DAIDS-0029 will be available electronically on or about October 1, 1999, and may be accessed through the NIAID Contract Management Branch (CMB) Home Page by using the following electronic address and instructions: NIAID/CMB Home Page (via the WWW): Use http://www.niaid.nih.gov/contract to access the NIAID/CMB Home Page. Once at the NIAID/CMB Home Page, click on the "RFPs" link and then click on "RFP NIH-NIAID-DAIDS-00-29." Please note that the RFP for this acquisition has been revised to include only the Work Statement, Deliverable and Reporting Requirements, and Special Requirements, if any, the Technical Evaluation Criteria, and the Specific RFP Instructions and Provisions. All information required for the submission of an offer will be contained in the electronic RFP package. Following proposal submission and the initial review process, Offerors comprising the competitive range will be requested to provide additional documentation to the Contracting Officer. Responses to this RFP will be due on December 30, 1999. Any responsible Offeror may submit a proposal which will be considered by the Government. This advertisement does not commit the Government to award a contract. Point of Contact: Ross Kelley, Contract Specialist Electronic mail address: rk17a@nih.gov Telephone: (301) 402-2234 FAX: (301) 402-0972 Posted 09/14/99 (W-SN379927). (0257)

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