Los Alamos National Laboratory, Mail Stop C334, P.O. Box 1663, Los Alamos, NM 87545

A -- BIOSENSOR FOR THE DETECTION OF CHEMICAL AND BIOLOGICAL AGENTS SOL LAUR-99-6133 DUE 121599 POC John B. Mott, Los Alamos National Laboratory, Civilian & Industrial Technology Program Office, PHONE (505) 665-0883, FAX (505) 665-6127, EMAIL jmott@lanl.gov E-MAIL: jmott@lanl.gov, jmott@lanl.gov. The University of California, which operates Los Alamos National Laboratory (LANL) under contract to the U.S. Department of Energy, solicits Letters of Interest from companies interested in obtaining license rights to commercialize a biosensor for the detection of chemical and biological agents ("Technology"). The Technology makes use of competitive binding of a target molecule to a recognition ligand; upon binding there is a release of fluorescent or electrochemical quenching that produces a detectable signal. The Technology is embodied in a provisional patent application filed with the U.S. Patent and Trademark Office in May 1999. In order to successfully commercialize this Technology, the licensee(s) may need to collaborate with LANL staff; therefore, close proximity to LANL may be advantageous. Any company interested in licensing the Technology must respond with a Letter of Interest that provides a description of the company's (1) business and business goals; (2) managing officers and board of directors; (3) technical staff and resources; (4) financial resources; (5) manufacturing and marketing capabilities; and (6) motivation for pursuing this opportunity. Respondents are encouraged to provide ancillary documentation such as annual reports, corporate resumes, commitment letters from financial partners, and technical publications. The Letter of Interest must provide this information or the respondent will not be considered as a qualified respondent. The Letter of Interest must be received on or before December 15, 1999. Qualified respondents will be required to submit a comprehensive business plan. Please send Letters of Interest to the attention of John B. Mott, Los Alamos National Laboratory, Civilian & Industrial Technology Program Office, Mail Stop C334, Los Alamos, New Mexico, 87545. For further information contact Dr. Mott by phone [505-665-0883], fax [505-665-6127], or email [jmott@lanl.gov]. Posted 11/16/99 (W-SN401134). (0320)

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