National Institutes of Health, National Institute of Allergy and Infectious Diseases, Contract Management Branch, Room 2230, 6700-B Rockledge Drive, MSC 7612, Bethesda, MD 20892-7612

A -- ANIMAL MODELS OF HUMAN VIRAL INFECTIONS FOR EVALUATION OF EXPERIMENTAL THERAPIES SOL NIH-NIAID-DMID-01-03 DUE 122399 POC Nancy Hershey, Contracting Officer, (301) 496-0193 The Virology Branch (VB) of the Division of Microbiology and Infectious Diseases (DMID), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH) has a requirement to provide services and facilities to support animal models of clinically important human viral infections for evaluation of experimental therapies for NIAID. The purpose of this Request for Proposal is to seek responsible offerors for providing services and facilities for these animal models and to evaluate experimental therapies for potential in vivo efficacy (therapeutic and/or prophylactic) and toxicity in animals. Models for cytomegalovirus, herpes simplex, orthopoxvirus, respiratory syncytial virus, and influenza infections are a priority for NIAID, but offerors are also encouraged to propose models for other viral infections as well. Models for viral hepatitis, retrovirus, and papillomavirus infections are not eligible for this solicitation since they are supported separately by the NIAID.It is anticipated that four (4) cost-reimbursement, completion-type contracts will be awarded for a period of seven years, beginning approximately September 15, 2000. RFP-NIH-NIAID-DMID-01-03 will be available electronically on or about December 23, 1999, and may be accessed through the NIAID Contract Management Branch (CMB) Home Page by using the following electronic address and instructions: NIAID/CMB Home Page (via the World Wide Web): Access by using http://www.niaid.nih.gov/contract and select the "RFPs" link and then select "RFP-NIH-NIAID-DMID-01-03." Please note that the RFP for this acquisition has been revised to include only the Statement of Work, deliverable and reporting requirements, special requirements and mandatory qualifications, if any, the Technical Evaluation Criteria, and the proposal preparation instructions. All information required for the submission of an offer will be contained in the electronic RFP package. Following proposal submission and the initial review process, offerors comprising the competitive range will be requested to provide additional documentation to the Contracting Officer. Responses to this RFP will be due April 15, 2000. Any responsible offeror may submit a proposal which will be considered by the Government. All inquiries must be in writing and addressed to the office below: Point of Contact: Nancy Hershey Contract Management Branch National Institute of Allergy and Infectious Diseases National Institutes of Health Room 2230 6700B Rockledge Dr., MSC 7612 Bethesda, Maryland 20892-7612 Electronic Email: nh11x@nih.gov Fax: (301) 480-5253 All respondents are asked to indicate the type and size of your business organization, e.g., Large Business, Small Business, Hubzone Small Business, Small Disadvantaged Business, Women-Owned Business, 8(a), Historically Black College or University/Minority Institution (HBCU/MI), educational institution, profit/non-profit hospital, or other nonprofit organization. This advertisement does not commit the Government to award a contract. No collect calls will be accepted. Posted 12/08/99 (W-SN406889). (0342)

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