National Institutes of Health, Office of Procurement Management, 6011 Executive Blvd., Rockville, Maryland 20892-7260

66 -- LASER SCANNING CONFOCAL FLUORESCENCE MICROSCOPE SYSTEM SOL 263-00-B(BC)-0008 POC Sheri Custer, Contracting Officer on 301-402-3065 or Edward Wilgus, Chief, Acquisitions Branch B, on 301-402-3070 This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; bids are being requested and a written solicitation will not be used. The solicitation number is 263-00-B(BC)-0008 and is issued as an Invitation for Bid (IFB). The solicitation/contract will include all applicable provisions and clauses in effect through FAC 97-14. The standard industrial code (SIC) is 3826 and the size standard is 500 employees. This is not a small business set aside. (A) The National Institutes of Health, National Institute of Aging (NIA), has a requirement for a laser scanning confocal fluorescence microscope system. This system shall include, but not be limited to, the following performance characteristics, features, and pertain to the following components: (1) Confocal fluorescence microscope system with the following lasers or better: 25 mW Argon laser -- 458, 488, 514 nanometers 80 mW Argon laser -- 351, 364 nanometers 50 mW Argon Krypton laser -- 488, 568 nanometers, low noise capabilities 5 mW Helium Neon laser -- 633 nanometers 1 mW Helium Neon laser -- 543 nanometers (2) This system shall offer low maintenance and high reliability. Affords proven performance with positive support from the scientific community. Shall afford coupling of the system to an inverted microscope; (3) Scan control shall incorporate dual galvanometer mirrors and be accomplished digitally, analog techniques are unacceptable. Scan rotation of 360 degrees shall be provided; (4) Visible and ultraviolet acousto-optical filtering shall be used to allow rapid light switching; (5) Instrument shall be capable of both 8 bit and 12 resolution; (6) Instrument shall use fiber optic coupling of all lasers to the scan unit; (7) Provides for a high resolution Z-stage. Galvanometric stage shall afford high precision. The step size shall be 10 nanometers or better, with accuracy of 30 nanometers over a travel range or 200 micrometers or better; (8) Individual pinholes shall be required for detectors. Shall afford continuously variable size and position adjustment through the use of computer control; (9) Three or more simultaneous photomultiplier channels shall be req1uired; (10) System shall be fully motorized including beam splitters, emission filters, pinhole adjustment, and excitation wavelength selection is under computer control; (11) Shall be configurable with up to 4 detectors for fluorescent or reflected light imaging. All 4 channels shall be displayable and recordable simultaneously; (12) Image size shall be user selectable up to 2K X 2K pixels or better; (13) Field size shall be up to 18 millimeters or better (1X zoom, Plan-Neofluar 1.25 X /0.04 objective); (14) Shall include provisions for the elimination of crosstalk between channels for specimens with multiple labels, (15) Laser intensity shall be monitored to provide correction(s) for laser fluctuations; (16) Focus function shall afford 100 nanometer resolution with 100 nanometer reproducibility; (17) Shall provide the capability of acquiring images using three different laser lines simultaneously; (18) Shall include a Windows NT operating system. Visual basic interface for customization shall be provided; (19) The system computer shall provide a Pentium II at 400 MHz or better processor, 256mb of RAM, 4 Gb hard drive, and includes support for dual monitors for 2560 X 1024 display, or better. Shall include Iomega Zip drive; (20)Physiological software for acquisition and control shall be required; (21) The following lettered list shall also be included: (a) Transmitted light channel, (b) Monitor diode, (c) Anti vibration table, (d) Guardrail 30", 36", 48", (e) Mechanical stage (85 x 130) with mounting frame, (f) Plastic dust cover, (g) Extension cable for 100 W illuminator. (h) Two (2) Hal. 12V 100W with sq. fil., I Stab. Power supply 12V 100W, (i) Illuminator carrier, (j) Remote cable for illuminator, (k) Reflector sldr3FL, (l) Refl LT equipment, (m) Two (2) burners HBO 50W/L2, (n) Power Supply for HBO 50AC with digital meter, (o) UV filter set, (p) FITC filter set, (q) Rhodamine set, (r) LD cond. 0.55H/3D/PH1-3/DIC.DID, (s) Binoc phototube 45/20 100/100, (t) Universal mounting frame k, (u) Hal-illmtr 100W /hous/coll/sock, (v) Conversion filter 3200/5500 32, (w) Lamp housing hbo 50 w/socket, (x) 3 lens collector F, (y) Plan-neo 10x/0.30 WD-5.6MM, (z) Dic slider F/10x/0.30, (aa) Two (2) eyepiece E-PL 10x/20 FOC/26DIA, (bb) Two (2) folding eyecup, (cc) Plan-neo 25x/0.8 IMM. corr dic, (dd) Dic slider F/25x/0.80 IMM, (ee) Plan-apo 63x/1.4 oil h/dic, (ff) Dic slider F/63x/1.40 oil, (gg) C-apochromat 40x/1.2 W corr, (hh) Dic slider F/C-apo 40x, (ii) Dic prism 0.3-0.4/0.55; and (22) The system shall be compatible with existing Carl Zeiss Inc. equipment which has been previously acquired. (B) DELIVERY AND INSTALLATION: System delivery (inside) prior to, and installation (set-up) during the week of, March 6-11, 2000 is required. (C) TERMS AND CONDITIONS: This shall be a fixed price, definite delivery contract. (D) EVALUATION: (1) A technical proposal is not required if this bid is for a catalog item. However, sufficient descriptive literature and a catalog must be submitted with the bid to enable an evaluation against the specifications; (2) The Government will award a contract resulting from this solicitation to the lowest responsive and responsible bidder meeting the salient characteristics/specification. A published catalog price list must be submitted with the bid to determine the reasonableness of the proposed price (3) A list of three (3) contracts/projects performed for the Government that involved similar or related work to that called for in this IFB. Include the contract number, involved agency, cost, Contracting and Projecting Officers, contact person's name, telephone number and (4) In accordance with FAR 52.214-21 Descriptive Literature shall be submitted with the IFB. The bid with a catalog shall address the evaluation criteria, a pricing and published price list shall include the pricing for each of the areas in paragraph A above and a completed copy of the FAR provision 52.212-3, Offeror Representations and Certifications Commercial Items, are required as part of the IFB. The following clauses are applicable to this acquisition: FAR 52.212-4 Contract Terms and Conditions-Commercial Items, FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders-commercial Items, and FAR 52.212-1 Instructions to Offerors-Commercial Items. Final payment will be issued when all requirements of the contract have been completed to the satisfaction of the Contracting Officer and the Project Officer. IFBs are due in the designated contracting office by 1:00 p.m. local time, December 29, 1999. IFB must be in writing and addressed as follows: (a) If mailing your proposal through the U.S. Postal Service use the following address: National Institutes of Health, Office of Procurement Management, OA, 6011 Executive Blvd., Room 529Q, MSC 7663, ATTN: Sheri Custer, Bethesda, MD 20892-7663; (b) If hand delivering, or using a courier service such as: UPS, Federal Express, etc., use the following City, State and Zip Code: Rockville, MD 20852. Delivery of proposals may be made Monday through Friday, between 8:30 a.m. and 5:00 p.m. (local time). Any questions please call Sheri Custer on 301-402-3065. Posted 12/13/99 (W-SN407947). (0347)

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