National Institute of Diabetes, Digestive & Kidney Diseases (NIDDK), Acquisition Management Branch, Natcher Building, 45 Center Dr., MSC 6600, Room 6AN32, Bethesda, Maryland 20892-6600

Q -- UNIGEM V SERVICE (HUMAN)MOUSE GEM I SERVICE AND GEMTOOLS SOFTWARE SOL RFQ-NIDDK-00-517 DUE 011200 POC Desiree Kelly, Purchasing Agent 301-594-7731 The National Institutes of Health (NIH), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has a requirement to purchase UniGEM V Service(human) Mouse GEM I Service and GEMTools Software from Genome Systems Inc., 3174 Porter Drive, Pala Alto, CA 94304. The following specifications shall be included in the laboratory services. Data should be formatted for GEMTools software analysis unless a written request for an alternative text format is provided to Incyte prior to the hybridization. Incyte control elements on each array will be used to determine the validity of each assay. Data should be provided within 20 working days from receipt of 2 samples mRNA at Incyte, or 30 working days for 2 total RNA samples. The government will provide two RNA samples to compare the level of gene expression in two biological samples. The vendor will provide labeling, hybridization and data analysis of the samples hybridized. The Array services will use high density arrays using up to 10,000 elementswith two color hybridization technology. The data, including a comparison of the level of gene expressions in both samples, will be provided as web based data. The Institute intends to purchase this service by other than full and open competition from Genome Systems Inc. To the best of the Governments knowledge they are the sole manufacturer and distributor of this service. This notice of intent is not a request for competitive proposals, however, all responses received before the closing date of this announcement will be considered by the Government. A determination by the Government not to compete this proposed acquisition is based upon responses to this notice and is solely within the discretion of the Government. Information received will be considered solely within the discretion of the Government. It is anticipated that Request for Quotation (RFQ) NIH-NIDDK-00-517 will be available fifteen (15) days after the publication date of this synopsis. Receipt of quotations will be due ten (10) days after the publication date of this synopsis. Receipt of award date is January 12, 2000. Request for copies of the RFQ must be in writing to the National Institute of Diabetes and Digestive and Kidney Diseases, 6705 Rockledge Drive, Building One, Room 8048, Bethesda, Maryland 20817-7973 Attention: Desiree Kelly. FAX quotations will only be accepted if dated and signed by an authorized company representative. Posted 12/16/99 (W-SN409293). (0350)

Loren Data Corp. http://www.ld.com (SYN# 0060 19991220\Q-0001.SOL)