National Institutes of Health, Office of Procurement Management, 6011 Executive Blvd., Rockville, Maryland 20892-7260

66 -- INSTRUMENTS & LABORATORY EQUIPMENT SOL 263-00-P(GQ)-0014 DUE 012500 POC Dorothy Nickens, (301) 496-0301 This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. The solicitation number 263-00-P(GQ)-0014 is issued as a Request for Proposal (RFP). The solicitation/contract will include all applicable provisions and clauses in effect through Federal Acquisition Circular (FAC) 90-14. The Standard Industrial Classification Code is 3826 and the business size is 500 employees. The National Institutes of Health, National Institute of Aging (NIA) in Baltimore, Maryland has a requirement for a real time digital fluorescence analyzer system. The NIH intends to contract with Carl Zeiss, Inc, One Zeiss Drive, Thornwood, NY 10594. The NIH believes that Carl Zeiss is the only known source that can meet the requirements. However, this requirement is not set-aside for small businesses. Any other firm that believes that it can meet the below specifications may submit an offer to National Institute of Health. This requirement is for a real time digital fluorescence analyzer system. This system shall include, but not be limited to, the following performance characteristics, features, and pertain to the following components: Shall perform analysis of fluorescent probes in living cells and preparations. Shall be capable of visualizing ions in real time. Ions shall be observable individually or simultaneously, only the types of probes in use shall limit combinations. Shall include image intensified CCD (ICCD) and high resolution digital cameras. Shall include motorized inverted microscope and confocal module. Shall provide for simultaneous fluorescence and brightfield image acquisition. Shall include the capability for three ratio images per second in dual excitation configuration with a standard wavelength selector or better. Shall provide for ten ratios per second in staticratio imaging mode or better. Shall include upper and lower gray-value threshold functions. Shall provide for online background correction, ratio display, and shading correction functions or better. Shall provide for static ratio imaging and image averaging. Full frame ratio imaging shall be supported. Shall include image integration for very low light experimentation. Shall include provisions for data calibration. Shall include automated and interactive image storage. Shall include support for up to 99 regions of interest or better. Shall include experimental log and timer. Shall support stored image sequence analysis. Shall include software to integrate data and images. Shall include Z focus control. Shall be capable of performing ion studies in confocal mode in cells or tissues. The system shall be capable of providing three-dimensional image stacks of multiple probes. This shall allow for investigation of the structure and co-localization of antibodies. Shall support non-laser confocal fluorescence. Shall support ultraviolet and visible excitation wavelengths. Shall include PC based software for controlling the microscope hardware and digital imaging system. Shall include a Personal Computer with the following features, or better: Windows 98 software, 450MHz Pentium III processor, 128 megabytes of RAM, Two 17 inch monitors, Read/Write CD-ROM drive, Zip drive, LAN capable. The system shall be complete and perform the functions for which for which it was intended. All necessary interconnection cabling, documentation, and support after installation shall be provided. The system shall be compatible with existing Carl Zeiss Inc. equipment which as been previously acquired. Delivery shall be F.O.B. Destination, inside delivery and the equipment shall be delivery 60 days after contract award. The Government will evaluate based on F.O.B. Destination, and acceptance in Baltimore, Maryland and the requirement of FAR 52.214-21 "Description Literature" apply. Information provided must demonstrate the equipment's abilityto meet the specifications described herein. Award will be made to the technically acceptable low offer. A complete copy of the provision FAR 52.212-1, Instructions to Offerors-Commercial Items and a complete copy of the provision FAR 52.212-3, Offeror Representations and Certifications-Commercial Items is required as part of the offer. The latter provision includes the DUNS Number Addendum. The resulting contract will incorporate the requirements of the clause at FAR 52.212-4, Contract Terms and Conditions-Commercial Items, and the clause at FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders -- Commercial Items. The following clauses are also applicable to this acquisition: FAR 52.222-26, Equal Opportunity; FAR 52.222-35, Affirmative Action for Special Disabled and Vietnam Era Veterans; FAR 52.222-36, Affirmative Action for Workers with Disabilities; FAR 52.222-37, Employment Reports on Special Disabled Veterans and Veterans of Vietnam Era; and FAR 52.225-3, Buy American Act-Supplies. Full text copies of the representations and certifications or other cited provisions and clauses may be obtained by http://www.arnet.gov/far/. A completed and signed "offeror Representation and Certifications-Commercial Items -- with DUNS Number Addendum must accompany offers. Descriptive literature, warranties and/or materials that demonstrate that the offer meets the stated requirements must also accompany offers. Information furnished should include enough material to conduct a proper evaluation. The Contractor will be paid following delivery and acceptance of the equipment. Sources demonstrating the capability to accomplish the above shall provide pertinent information that is in sufficient detail to demonstrate their ability to perform within 15 days of this notice. A determination by the Government not to complete this proposed contract based upon the responses to the notice is solely within the discretion of the Government. The proposed contract action is for supplies or services for which the Government intends to solicit and negotiate under the Authority of Far 6.302. Respondents will not be notified of the evaluation results. Address responses to the attention of Dorothy Nickens. If mailing your proposal through the U.S. Postal Service, use the following address: National Institute of Health, Office of Procurement Management, 6011 Executive Blvd., Room 529M, Bethesda, Maryland 20892-7663. If hand delivering or using a delivery services (e.g. Federal Express) use the following address: National Institutes of Health, Office of Procurement Management, 6011 Executive Blvd., Room 529M, Rockville, Maryland 20852-7663. Posted 01/10/00 (W-SN414518). (0010)

Loren Data Corp. http://www.ld.com (SYN# 0220 20000112\66-0005.SOL)