Bechtel BWXT Idaho,LLC, P.O. Box 1625, Idaho Falls, ID 83415-3521

A -- TREATMENT PLANNING METHOD AND SOFTWARE FOR TARGETED RADIONUCLIDE THERAPY AND BRACHYTHERAPY SOL Cbd0400 DUE 021400 POC Alan Davis WEB: Idaho National Engineering & Environmental Laboratory, http://www.inel.gov/procurement/litco/index.html. E-MAIL: Alan Davis, daviaj@inel.gov. A-Treatment planning method and software for targeted radionuclide therapy and brachytherapy. Bechtel BWXT Idaho, LLC, (BBWI) the prime operating contractor for the Department of Energy (DOE) at the Idaho National Engineering & Environmental Laboratory (INEEL) has developed a new treatment planning software technology for use in neutron radiotherapy that also has potential applications in standard photon radiotherapy. The subject software offers an accurate, and very fast, medical-image-based method for computation of therapeutic radiation dose distributions. Unique features of the technology include sophisticated pixel-based patient geometry reconstruction from medical images as well as integer-based numerical geometric interrogation coupled with appropriate full three-dimensional Monte-Carlo based radiation transport modules. This permits precise, patient-specific target and peripheral organ definition and extremely fast numerical computations of radiation flux and dose distributions. This software is used for therapy planning in clinical Boron Neutron Capture Therapy and it will be introduced for use in fast-neutron therapy over the next year or so. With some relatively straightforward modifications, the software could be adapted for use in standard external-beam photon radiotherapy, targeted radionuclide therapy, and brachytherapy. This would create a fast-running (~5 minutes per field on single-CPU pentium-type equipment) treatment planning system that has full three-dimensional Monte Carlo capabilities. BBWI is seeking a commercial partner to sponsor the necessary modifications to the software in return for specified exclusive commercial rights to the modified product. This is not an opportunity to provide goods or services to BBWI or the Department of Energy. This Request for Interest (RFI) will close to response 30 days after publication. Interested parties should send e-mail to daviaj@inel.gov (Alan Davis, Account Executive, Technology Transfer Office, BBWI). If you do not have e-mail access, send regular mail to Alan Davis, Account Executive, Technology Transfer Office, BBWI, P. O. Box 1625, Idaho Falls, ID 83415-3805. Posted 01/12/00 (W-SN415502). (0012)

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