Director, USAMRAA, 820 Chandler St, Fort Detrick, MD 21702-5014

A -- GULF WAR ILLNESSES RESEARCH: BIOCHEMICAL AND PHYSIOLOGICAL MARKERS TO ASSESS TOXIC CHEMICAL EXPOSURES AND HEALTH EFFECTS IN DEPLOYED MILITARY PERSONNEL SOL CBD-GWI-0200 POC Craig D. Lebo, Contracting Officer, 301-619-2036 The U.S. Army Medical Research and Materiel Command is soliciting proposals for studies for applied physiologically based methods and techniques for assessment of toxic chemical exposures in deployed military personnel. The research should improve current methods and techniques or identify and develop new, readily applied, methods and techniques. Specifically, studies must identify and develop biological markers of exposure that enhance environmental monitoring or provide markers of effect related to exposures of individual service members. Methods and techniques should be applicable to risk assessment or health surveillance of toxic chemicals and chemical mixtures that are a concern in military deployments. Specific chemicals of interest include petrochemical products (including JP8 fuel), insecticides, insect repellents, and Chemical Agent Resistant Coating (CARC). Proposals must provide a clear justification and military relevance. Submission of preliminary data is encouraged. Collaborations with DoD medical researchers are encouraged. Awards are expected to average $200K per year for up to four years of support. A total of approximately $5M will be made available for studies in this topic. Proposals should be submitted according to general instructions contained in the Broad Agency Announcement 99-1 (see http://www-usamraa.army.mil). Preproposals are not required; letters of intent (LOI) containing a proposed title, brief description of project scope (<150 words), and investigator and institution identification are due by 14 June 2000. These LOI will be used to plan the review process. Do NOT expect a response to your LOI. Full proposals are due no later than 4 p.m., EST, 26 July 2000. Send letters of intent and proposals to: Commander, U.S. Army Medical Research Acquisition Activity, ATTN: GWIRP2000, 820 Chandler Street, Fort Detrick, MD 21702-5014. Posted 02/16/00 (W-SN425845). (0047)

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