National Institutes of Health, National Institute of Allergy and Infectious Diseases, Contract Management Branch, Room 2230, 6700-B Rockledge Drive, MSC 7612, Bethesda, MD 20892-7612

A -- HLA TYPING AND EPITOPE MAPPING TO GUIDE HIV VACCINE DESIGN SOL RFP NIH-NIAID-DAIDS -- 01-09 DUE 063000 POC Dee Dee Moss, Contract Specialist, (301) 402-5825, fax (301) 480-5253, e-mail dg25a@nih.gov The National Institute of Allergy and Infectious Diseases (NIAID) supports a comprehensive portfolio of grant and contract resources to discover, develop and evaluate potential vaccines to prevent infections caused by Human Immunodeficiency Virus-1 (HIV-1). This contract shall support the immunogenetic characterization of selected HIV seropositive and seronegative populations at domestic and international vaccine sites, identify and map the CTL epitopes restricted by the common HLA types, analyze the HIV clade variants circulating in the geographic locations of the cohort to be immunized, and establish a database of HLA types, associated T cell epitopes, and viral variants to guide HIV vaccine design, prediction of immune responses and assay development. It is anticipated that one (1) cost reimbursement, completion type contract will be awarded for a period of five (5) years, beginning approximately February 1, 2001. RFP NIH-NIAID-DAIDS-01-09 will be available electronically on or about March 20, 2000, and may be accessed through the NIAID Contract Management Branch (CMB) Home Page by using the following electronic address and instructions: NIAID/CMB Home Page (via the WWW): Use http://www.niaid.nih.gov/contract to access the NIAID/CMB Home Page. Once at the NIAID/CMB Home Page, click on the "RFPs" link and then click on "RFP NIH-NIAID-DAIDS-01-09." Please note that the RFP for this acquisition has been revised to include only the Work Statement, Deliverable and Reporting Requirements, Special Requirements and Mandatory Qualification, if any, the Technical Evaluation Criteria, and the Specific RFP Instructions and Provisions. All information required for the submission of an offer will be contained in the electronic RFP package. Following proposal submission and the initial review process, Offerors comprising the competitive range will be requested to provide additional documentation to the Contracting Officer. Responses to this RFP will be due on or about June 30, 2000. Any responsible Offeror may submit a proposal which will be considered by the Government. This advertisement does not commit the Government to award a contract. Point of Contact: Dee Dee Moss, Contract Specialist Email: dg25a@nih.gov Telephone: (301) 402-5825 FAX: (301) 480-5253 No collect calls will be accepted. Posted 03/15/00 (W-SN434597). (0075)

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