National Cancer Institute, Research Contracts Branch, PSAS, 6120 Executive Blvd, EPS/Room 638, Bethesda, MD 20892-7227

66 -- FLUORESCENCE MICROSCOPE SYSTEM SOL RFQ-NCI-00087-NR DUE 040300 POC Marsha Gorham, Purchasing Agent & Gail Zois, Contracting Officer The National Cancer Institute (NCI), Molecular Tumor Biology Section of the Basic Research Laboratory Division of Basic Sciences intends to procure on a sole source basis for a Fluorescence Microscope System with Carl Zeiss, Inc, One Zeiss Drive, Thornwood, NY 10594. This system will replace an older Carl Zeiss system and approximately $20,000 of components from the aged Zeiss system will be needed to complete this system. In conjunction with components previously purchased from Zeiss, the proposed system will incorporated motorized XY and Z axis drives, transmitted and reflected light shutters along with a dual filter wheel for reflected light for automated excitation wavelength selection. The new system will be equipped with an environmental chamber and an existing digital camera/video capture system for experiments using time-lapse microscopy. An existing microinjector, which was custom configured to fit on a Carl Zeiss microscope, will be also attached to the microscope for microinjection experiments. New software OPENLAB (Mac based) will be used to control the entire system to achieve confocal microscopy-like performance. This includes a visual programming which makes it easy to set up and run a variety of experiments, making the system user friendly. The system also contains a cell tracking system, which allows the user to mark the positions of cells for later location. Therefore, it allows the user to identify unlimited random or regularly spaced locations for automatic scanning. These unique capabilities as well as interchangeability and compatibility are essential for proper operation and cost effective set-up on the proposed system. This notice of intent is not a request for competitive proposal. However, if any interested party believes it can meet the above requirement, they may submit a statement of capabilities. Information furnished must be in writing and must contain sufficient detail, to allow NCI to determine if the party can meet the requirement. Capability statement must be received in the Contracting Office by 2:00 PM EST on April 3, 2000. If you have any questions, please contact Marsha Gorham, Purchasing Agent (301)402-4509. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. Please reference RFQ-NCI-00087-NR on all correspondence and documentation. Posted 03/17/00 (W-SN435560). (0077)

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