National Cancer Institute, Research Contracts Branch, PSAS, 6120 Executive Blvd, EPS/Room 638, Bethesda, MD 20892-7227

66 -- DIGITAL IMAGING SYSTEM SOL RFQ-NCI-00082 DUE 040700 POC Cynthia Brown, Purchasing Agent, 301-402-4509, Gail Zois, Contract Officer The National Institutes of Health, National Cancer Institute (NCI), Laboratory of Cell Biology intends to procure on a sole-source basis with Carl Zeiss Inc., One Ziess Drive, Thornwood, NY 10594 under the authority of 41.U.S.C. 253 (c)(1), FAR 6.302-1 a Digital Imaging System. The Laboratory of Cell Biology studies the processing, transport and metabolism of proteins and small molecules, especially those related to cancer prevention, development and treatement. Advanced digital imaging capabilities that are an essential part of this research program will enhance the investigation of intracellular interactions of mammalian ATPase VCP, a protein of the AAA family, a family of intracellular ATPases involved in protein transport, vesicular and organellar fusion, and is also a component of the 20S proteosome. The Digital Imaging System must be equipped with the following salient characteristics: 1) capable of achieving very high resolution at High (x 1000) magnification; 2) achieve very high sensitivity tolow level fluorescence with the simultaneous ability to attenuate high fluorescence levels; 3) the system shall allow the user to configure the control functions of the software to existing system; 4) capable of storing all images, measurements, annotation overlays and time information from an experiment in one storage location; 5) the system shall allow the user to select colors corresponding to exact wavelengths so that fluorescence images will look as they do in the microscope; 6) the system shall achieve very high focusing resolution of the Z-axis and be 100% compatible with Apple Macintosh G4 Computers. It is the government's belief that these requirements can only be met by Carl Zeiss Inc., Thornwood, New York. This is not a request for competitive quotation, however, if any interested party believes it can meet the above requirement, they may submit a statement of capabilities. Information furnished must be in writing and must contain sufficient detail, to allow NCI to determine if the party can meet the requirement. Capability statements must be received in the Contracts Officer by 2:00 P.M. EST on April 7, 2000. If you have any questions, please contact Cynthia Brown, Purchasing Agent on (301) 402-4509. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. Please referece RFQ-NCI-00082. Posted 03/21/00 (W-SN436528). (0081)

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