U.S. Environmental Protection Agency, National Exposure Research Laboratory, 79 Alexander Drive, MD-78A, Research Triangle Park, NC 27711

A -- EPA COLLABORATION WITH ON-GOING RESEARCH TO ASSESS CHILDREN'S EXPOSURE TO PESTICIDES AFTER A PROFESSIONAL APPLICATION IN THE HOME OR DAYCARE SOL NERL/HEASD/FY00-02 DUE 041700 POC Shari Pricer, 919-541-2198 E-MAIL: Click here to email the contact person, pricer.shari@epa.gove. The United States Environmental Protection Agency's (EPA) Office of Research and Development (ORD), National Exposure Research Laboratory (NERL), located in Research Triangle Park, NC, is seeking opportunities for co-sponsoring on-going research. EPA is seeking a collaborative effort with one or more research institutions engaged in studies characterizing pesticide exposures to children. This is not a request for new research proposals. The program is seeking collaboration with researchers who are already planning or conducting studies to assess children's exposures to pesticides. We anticipate enhancing current study designs to collect additional exposure data on the time course of pesticide distributions following a professional pesticide application, and, to assist in the development of dermal transfer coefficients for children within specific age groups in specific microenvironments and macroactivities. Specifically, EPA is seeking one or more research opportunities for collecting new exposure datathat will be beneficial to the recipient, the scientific community, and EPA, in the following areas: (a) the distribution, redistribution, and resuspension of pesticide residues throughout the home or daycare following a professional application, (b) a description of the microenvironments where children spend the majority of their time and the macroactivities in which children are the most involved, (c) the fraction of the pesticide residue that may be transferred from a surface or object to a child by a specifically defined macroactivity, and, (d) the dermal transfer coefficients associated with the specified macroactivities. Collection of these data will allow EPA, the collaborators, and the scientific community to test the feasibility of various approaches for assessing dermal and non-dietary exposures to children. Research should focus specifically on children within well-defined age groups. The study may require measurements on the temporal and spatial distribution of the applied pesticide in the home and/or daycare setting. In response to this sources sought synopsis, EPA is requesting a copy of the current study designs and data analysis plans from interested domestic not-for-profit or non-profit research institutions such as universities, research institutes, and federal research laboratories. Opportunities to enhance studies being planned and conducted by for-profit organizations may also be considered. This is not a solicitation for a full Request for Application (RFA) or Request for Proposal (RFP). If responses to this sources sought synopsis indicate that there are one or more good possibilities for collaboration, EPA will decide whether to initiate a competitive or non-competitive vehicle. Study designs and data analysis plans should be postmarked by April 17, 2000 and sent to Shari Pricer, U.S. EPA, National Exposure Research Laboratory, MD-78A, 79 T.W. Alexander Dr., Research Triangle Park, NC 27711 (email: pricer.shari@epa.gov). Posted 03/23/00 (W-SN437453). (0083)

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