National Institute of Diabetes, Digestive & Kidney Diseases (NIDDK), Acquisition Management Branch, Natcher Building, 45 Center Dr., MSC 6600, Room 6AN32, Bethesda, Maryland 20892-6600

B -- RESEARCHER WITH EXPERIENCE IN BIOSTATISTICAL SERVICES FOR A ONE YEAR PERIOD WITH TWO YEAR OPTIONS FROM HARVEY KUSHNER SOL NIH-NIDDK-00-546 DUE 042400 POC Desiree Kelly, Purchasing Agent 301-594-7731 The National Institutes of Health (NIH), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has a requirement to purchase the services of a researcher with experience in Biostatistical Services for a one year period of performance with (2) two successive one year options from Harvey Kushner, Biomedical Computer Research Institute, 9743 Redd Rambler Place, Philadelphia, PA. This study is designed to investigate in African Americans the relationship of obesity to coronary artery disease risk factors, specifically fasting plasma triglyceride concentration and the triglyceride related risk factors of small dense low density lipoprotein (LDL), high density lipoprotein (HDL) and visceral fat. NIDDK is conducting clinical research related to the causes and therapy of diabetes and related diseases. Considerable statistical expertise is required to design clinical studies and to analyze data derived therefrom. The following requirements must be met: 1) Advice on current study design 2) Statistical evaluation and interpretation of preliminary data 3) Design of future studies using current data as pilot data 4) Database management and data entry 5) Biostatitical analysis (both theoretical and computer-based) 6) Providing "hard copy" data reports, and data analyses 7) Assistance in writing manuscripts (with respect to components related to statistical analysis) 8) Quality control for data entry and data management. The Government will provide data (hard copy) written on forms approved by both Clinical Investigators in NIDDK and the contractor. The Governments responsibility to assure the accuracy of data recorded on these forms. The Institute intends to purchase this service by other than full and open competition from Harvey Kushner, Biomedical Computer Research Institute. To the best of the Governments knowledge they are the sole provider for this service. Interested vendors may identify in writing their interest with a capability statement to the Contracting Office p rior to the closing date of this notice. This notice of intent is not a request for competitive proposals, however, all responses received before closing date is this announcement will be considered by the Government. A determination by the Government not to compete this proposed acquisition is based upon responses to this notice and is solely for the purpose of determining whether to conduct a competitive procurement. All responsible small business and (8)a sources may submit a quotation which, if timely received, shall be considered by the agency. It is anticipated that Request for Quotation (RFQ) NIH-NIDDK-00-546 will be available fifteen (15) days after the publication date of this synopsis. Receipt of quotations will be due ten days (10) after the publication date of this synopsis. The anticipated award date is April 24, 2000. Request for copies of the RFQ must be in writing and may be faxed to 301-480-4226. Quotations must be submitted in writing to the National Institute of Diabetes and Digestive and Kidney Diseases 6705 Rockledge Drive, Building One, Room 8048, Bethesda, MD 20817-7973. Attention: Desiree Kelly. Fax quotations must contain offerors names, address, and telephone number and fax number. Fax quotations will only be accepted if dated and signed by an authorized company representative. Posted 03/28/00 (W-SN438815). (0088)

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