National Institute on Drug Abuse, Contracts Management Branch, 6001 Executive Blvd., Room 3105, MSC 9543, Bethesda, MD 20892-9543

A -- PHARMACOKINETIC AND PHARMACODYNAMIC STUDIES FOR MEDICATION DEVELOPMENT SOL N01DA-0-8807 DUE 061700 POC Dale Weiss, Contracting Officer, 301-443-6677, Email dw79f@nih.gov The National Institute on Drug Abuse (NIDA) is soliciting proposals from qualified organizations having the capability to carry out clinical studies to determine the pharmacokinetics and pharmacodynamics of new medications for treating drug addictions in humans. The data obtained will be submitted to the Food and Drug Administration (FDA) in support of INDs (Investigational New Drugs) and NDAs (New Drug Applications). Offerors must indicate possession of current DEA registration for Schedule II-V substances prior to award and shall demonstrate either possession of or ability to obtain a DEA Research Registration for Schedule 1 under the controlled Substances Act of 1970. This work is currently being performed by the University of California, San Francisco under Contract N01DA-4-8306. NIDA anticipates that a 3-year cost reimbursement type contract (with options for 2 additional years, plus options for additional quantities), will result from this procurement. RFP No. N01DA-0-8807 will be available electronically on or about May 2, 2000, and may be accessed through the Internet at the following address: (URL: http://www.nida.nih.gov/RFP/RFPList.html) Please note that the RFP for this acquisition will be streamlined to include only the Work Statement, Deliverables and Reporting Requirements, Special Requirements and Mandatory Qualifications, Technical Evaluation Criteria, and other necessary Proposal Preparation Instructions. All information required for the submission of an offer will be contained in the electronic RFP package. Following proposal submission and the initial review process, offerors comprising the competitive range may be requested to provide additional documentation to the Contracting Officer. Response to the RFP will be due on or about June 17, 2000. Any responsible offeror may submit a proposal which will be considered by the Government. This advertisement does not commit the Government to award a contract. See numbered Note 26. Point of Contact: Dale S. Weiss, Contract Specialist Electronic Mail Address: dw79f@nih.gov Telephone: (301) 443-6677 Fax: (301) 443-7595 Posted 04/14/00 (W-SN445309). (0105)

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