National Institutes of Health, National Institute of Allergy and Infectious Diseases, Contract Management Branch, Room 2230, 6700-B Rockledge Drive, MSC 7612, Bethesda, MD 20892-7612

A -- SPECIALIZED IN VITRO IMMUNOLOGICAL EVALUATIONS OF STRATEGIES TO COMBAT HIV/AIDS SOL NIH-NIAID-DAIDS-01-18 DUE 080100 POC Ms. Lois Eaton, Contract Specialist, 301-496-0611 The Targeted Interventions Branch, Basic Sciences Program, Division of AIDS, National Institute of Allergy and Infectious Diseases (NIAID), NIH, has a requirement to provide in vitro immunologic evaluation for (i) the assessment of the quality and specificity of immunologic reagents of importance to AIDS clinical trials and preclinical studies; (ii) the evaluation of immunologic agents and strategies with potential anti-HIV activity; (iii) the examination of novel immune modulators for effects on HIV replication in vitro; and (iv) the evaluation of immune reactivities of patients receiving experimental anti-HIV therapies. These efforts will support a comprehensive portfolio of contract resources to discover and develop novel therapeutic agents for the prevention and treatment of infections caused by HIV and other infectious agents. It is anticipated that one (1) cost reimbursement, completion type contract will be awarded for a period of seven (7) years, beginning approximately March 31, 2001. RFPNIH-NIAID-DAIDS-01-18 will be available electronically on or about May 3, 2000, and may be accessed through the NIAID Contract Management Branch (CMB) Home Page by using the following electronic address and instructions: NIAID/CMB Home Page (via the WWW): Use http://www.niaid.nih.gov/contract/ to access the NIAID/CMB Home Page. Once at the NIAID/CMB Home Page, click on the "RFPs" link and then click on "RFP-NIH-NIAID-DAIDS-01-18." Please note that the RFP for this acquisition has been revised to include only the Work Statement, Deliverable and Reporting Requirements, Special Requirements and Mandatory Qualification, if any, the Technical Evaluation Criteria, and proposal preparation instructions. All information required for the submission of an offer will be contained in the electronic RFP package. Following proposal submission and the initial review process, Offerors comprising the competitive range will be requested to provide additional documentation to the Contracting Officer. Responses to this RFP will be due on August 1, 2000. Any responsible Offeror may submit a proposal which will be considered by the Government. This advertisement does not commit the Government to award a contract. Point of Contact: Lois W. Eaton, Contract Specialist Electronic mail address: le52u@nih.gov Telephone: (301) 496-0611 FAX: (301) 402-0972 No collect calls will be accepted. Posted 04/20/00 (W-SN447314). (0111)

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