National Cancer Institute, Research Contracts Branch, ESS, Executive Plaza South, Rm. 620, 6120 Executive Blvd., MSC 7224, Bethesda, MD 20892-7224

B -- STUDY CENTERS FOR CASE-CONTROL STUDY OF RENAL CELL CANCER AMONG CAUCASIANS AND AFRICAN AMERICANS SOL N02-CP-11004-66 DUE 072000 POC Shawnee J. Shaw, Contract Specialist, (301) 435-3778 WEB: Research Contracts and Acquisition Branch, http://amb.nci.nih.gov/. E-MAIL: Shawnee J. Shaw, SS552u@nih.gov. STUDY CENTERS FOR CASE-CONTROL STUDY OF RENAL CELL CANCER AMONG CAUCASIANS AND AFRICAN AMERICANS ELECTRONIC RFP ANNOUNCEMENT, POTENTIAL OFFERORS WILL BE RESPONSIBLE FOR DOWNLOADING THEIR OWN COPY OF THE SOLICITATION AND AMENDMENTS. The Division of Cancer Epidemiology and Genetics (DCEG), Epidemiology and Biostatistics Program (EBP)and Human Genetics Program (HGP), of the National Cancer Institute (NCI) is conducting a study to examine lifestyle, environmental, and genetic factors that may contribute to the increasing incidence rates of renal cell cancer in the United States and to the greater excess of this cancer among African Americans. This population based case-control study of renal cell cancer will be conducted in areas of the United States with a high proportion of African American residents. The following work will be conducted to support the population-based case-control study, including direct interview with a total of 700 African American cases and 1400 controls, and 1400 each of non-African American cases and controls from approximately 3-4 Study Centers over a case ascertainment period of approximately 3-4 years, as well as a brief interview with next of kin of eligible deceased cases. The contracts awarded as a result of this announcement will involve the following: 1) Study initiation and preparation of study materials; 2) Communication; 3) Case identification and recruitment; 4) Control identification and recruitment; 5) Review of study progress; 6) Data collection; 7) Data tracking, processing, and quality control; and 8) Deliverable and reporting requirements. A contract will be awarded for a Coordinating Center via another mechanism. This announcement is for the study centers covering residents of well-defined geographic areas in the United States. This procurement is a new project which is expected to cover a performance period of 60 months. The contracts to be awarded will be cost-reimbursement, completion. All responsible sources meeting these criteria are encouraged to submit an offer and will be considered by the National Cancer Institute. It is anticipated that the solicitation package will be available on /about July 1, 2000 with proposals due 30 calendar days after the issue date of the RFP. The RFP may be accessed via the NCI Research Contracts Acquisition Branch (RCAB) website: http://amb.nci.nih.gov/ under "Current Requests for Proposals". All responsible sources may submit a proposal which sahll be considered by the NCI. Award is anticipated by December 30, 2000. No collect calls will be accepted. Posted 06/13/00 (W-SN464049). (0165)

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