Los Alamos National Laboratory, Mail Stop C334, P.O. Box 1663, Los Alamos, NM 87545

A -- ULTRASENSITIVE BIOSENSOR FOR THE EARLY DETECTION OF THE PRESENCE OF THE INFLUENZA VIRUS SOL LAUR-00-3057 DUE 080700 POC Dr. John Mott by phone [505-665-0883], fax [505-665-0154], or email [jmott@lanl.gov] E-MAIL: jmott@lanl.gov, jmott@lanl.gov. The University of California, which operates Los Alamos National Laboratory (LANL) under contract to the U.S. Department of Energy, solicits Letters of Interest from companies interested in entering into a Cooperative Research and Development Agreement (CRADA) to develop and commercialize an ultrasensitive biosensor for the early detection of the presence of the influenza virus ("Technology"). The Technology is based on the detection of viral envelope proteins and is independent of virus type or subtype. The Technology is embodied in a provisional patent application filed with the U.S. Patent and Trademark Office on 28 October 1999. Interested companies must respond with a Letter of Interest that provides a brief description of the company's (1) business and business goals; (2) managing officers and board of directors; (3) technical staff and resources; (4) financial resources; (5) manufacturing and marketing capabilities; and (6) motivation for pursuing this opportunity. Respondents are encouraged to provide ancillary documentation such as annual reports, corporate resumes, and technical publications. The Letter of Interest must provide this information or the respondent will not be considered as a qualified respondent. The University will execute Nondisclosure Agreements with qualified respondents that will permit the exchange of information required to fully evaluate this opportunity. The Letter of Interest must be received on or before August 7, 2000. Please send Letters of Interest to the attention of John B. Mott, Los Alamos National Laboratory, Industrial Business Development Program Office, Mail Stop C334, Los Alamos, New Mexico, 87545. For further information contact Dr. Mott by phone [505-665-0883], fax [505-665-0154], or email [jmott@lanl.gov]. Posted 07/06/00 (W-SN471832). (0188)

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