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COMMERCE BUSINESS DAILY ISSUE OF AUGUST 8,2000 PSA#2659

DHHS/PHS/FDA/Office of Facilities, Acquisitions, And Central Services, Division Of Contracts and Program Management, HFA-511(ITCB), 5600 Fishers Lane, Rockville, MD 20857

B -- ARTHRITITS AFTER LYME VACCINE(T-CELL REACTIVITY) SOL A54147 DUE 081800 POC Ida Cofield, Contract Specialist, 301/827-7156, 301/827-7039 fax The Food and Drug Administration intends to issue a purchase order on a sole source basis to Tufts University School of Medicine to conduct a study regarding Arthritis after Lyme Vaccine (T-Cell Reactivity). The study will explore the association between DRB1*0401 and other RA associated HLA DRB1 alleles and arthritis after Lyme vaccine. In addition, the study will examine whether those with arthritis after Lyme vaccine have T-cells that are reactive to OspA and LFA-1. No solicitation will be issued, therefore, requests for such will be considered non-responsive. This purchase order is being issued on a sole source basis because the contractor is a leader in research among the Schools of Medicine in the U.S and has been a leader in research on Lyme disease. Posted 08/04/00 (W-SN482550). (0217)

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