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A -- EFFECTS OF SELECTIVE ESTROGEN RECEPTOR MODULATORS ON COGNITIVE AGING: THE STUDY OF TAMOXIFEN, RALOXIFENE AND COGNITION (STAR-COG) SOL NIH-AG-00-07 POC Teresa A. Baughman, Contracting Officer, 301-496-4487 E-MAIL: Click here to contact the Contracting Officer via, tb14j@nih.gov. The National Institutes of Health (NIH), National Institute on Aging (NIA), intends to negotiate a six year contract with Wake Forest University School of Medicine to collect ancillary data to the Study of Tamoxifen and Raloxifene (STAR). The data to be collected will include assessments of memory, cognition, and mood in older women who are participants of STAR. The data will allow the comparison of the effects of tamoxifen and raloxifene on cognitive aging. Wake Forest University is currently conducting a study under contract titled "Effects of Hormone Replacement Therapy on Cognitive Aging: Women's Health Initiative Study of Cognitive Aging (WHISCA). One of the goals of the proposed project is to compare cognitive outcomes in this project with those from WHISCA. Wake Forest University has the sole access to the sampling information and data on WHISCA participants, and only Wake Forest University has informed consent from the WHISCA participants to allow utilization of the data. The appropriate statutory authority is 41 USC 253(c)(1), as set forth in FAR 6.302-1(a)(2). This is NOT a Request for Proposal. If, however, there are any responsible sources who feel they possess the abilities which would enable them to perform this project, they may submit a proposal which will be considered by NIH. SEE NUMBERED Note 22.**** Posted 08/08/00 (W-SN483769). (0221)

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