Director, USAMRAA, 820 Chandler St, Fort Detrick, MD 21702-5014

A -- DEVELOPMENT OF A RICIN VACCINE CANDIDATE DUE 091100 POC Lynn Selfridge, Contracting Officer, (301) 619-2707; Mr. Richard Paul, JVAP PMO, (301) 619-7083 E-MAIL: Sources Sought for a Ricin Vaccine Candidate, Lynn.Selfridge@det.amedd.army.mil; Richard.Paul@det.amedd.army.mil. The Joint Vaccine Acquisition Program (JVAP) is seeking to identify information about candidates for a vaccine to protect against ricin (e.g., toxoid, deglycosylated, recombinant). The goal of the JVAP is to develop, license, and acquire an initial stockpile of vaccines to protect the U.S. Forces against biological warfare agents. Information about candidate ricin vaccines should include an outline of initial research and development of the product with any data supporting protective efficacy. A process for manufacture of the proposed ricin vaccine amenable to good manufacturing practices regulations is desirable. The developer must be willing to work with the JVAP's prime system contractor for continued process development, production, and FDA licensure of the ricin vaccine. Interested parties need to reply in writing to the address included in this sysnopsis. An acceptable response must include information regarding the research and development effort undertaken to this point, animal efficacy experiments, and any process development efforts. This sysnopsis is not a request for proposal; this is a notice to determine the level of interest and the capabilities available to meet the requirement of developing a ricin vaccine. Posted 08/08/00 (W-SN483847). (0221)

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