Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, CA 94550

A -- LAWRENCE LIVERMORE NATIONAL LABORATORY SEEKING INDUSTRIAL PARTNERS TO COMMERCIALIZE ITS HAND-HELD ADVANCED NUCLEIC ACID ANALYZER (HANAA) SOL CBD00-030 DUE 092500 POC Industrial Partnerships and Commercialization (925) 423-3139 Lawrence Livermore National Laboratory (LLNL), operated by the University of California under contract with the U.S. Department of Energy (DOE), is seeking one or more industrial partners to commercialize its Hand-held Advanced Nucleic Acid Analyzer (HANAA). The HANAA was developed to perform rapid polymerase chain reaction (PCR) analyses in the field. It contains four sample chambers, each with dual optical detection channels. The instrument measures 5 by 8 by 2 inches and weighs only 2 pounds. It can operate for 1.4 hours from a 2.5-pound battery pouch or longer with a larger battery belt. It has a keypad interface and is menu-driven through an LCD display. HANAA utilizes fluorescent Taqman detection and an advanced micromachined thermalcycler, which incorporates structural features that allow very rapid, accurate thermal cycling. The instrument is controlled by two microcontrollers and an embedded microprocessor. HANAA provides the first truly man-portable, handheld, field-capable, real-time PCR biodetection instrument. It is suited for military and civilian emergency response where biological pathogens are suspected and for field monitoring where a high level of portability is critical (e.g., monitoring water supplies for biological contamination in real time, or use in remote areas). It could also be used in standard medical applications where rapid diagnosis is needed but where more conventional instrumentation is not practical. Note: THIS IS NOT A PROCUREMENT. Parties interested in commercializing LLNL's HANAA technology should provide a written statement of interest including a commercialization plan and a description of corporate capabilities relevant to commercializing the technology. Written responses should be directed to: Lawrence Livermore National Laboratory Industrial Partnerships and Commercialization Office P.O. Box 808, L-795 Livermore, CA 94551 Attention: CBD00-030 Please provide your written statement within thirty (30) days from the date of this announcement, or by no later thanSeptember 25, 2000, to ensure consideration of your interest in commercializing HANAA technology. Posted 08/23/00 (W-SN489383). (0236)

Loren Data Corp. http://www.ld.com (SYN# 0002 20000825\A-0002.SOL)

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