B -- PRODUCTION AND DELIVERY OF SCHISTOSOMA MANSONI.

Notice Date

November 9, 2000

Contracting Office

Acquisitions Management Operations Branch, NIAID, 6700-B Rockledge Drive, Room 1130, Bethesda, MD 20892-7605

ZIP Code

20892-7605

Solicitation Number

NIAID-DIR-01-53

Point of Contact

Donna Baker, Contract Specialist or Karin Eddy, Contracting Officer, 301-496-3878

Description

The National Institute of Allergy and Infectious Diseases, NIH has a requireament for the production and delviery of adult worms and cercariae of Schistosoma mansoni. The successful offeror MUST be able to deliver worms and cercariae to the NIH campus in Bethesda, Maryland within 45 mininutes after they have been harvested to ensure viability. Approximately 2,000 adult S. mansoni shall be required each week. When different isolates are requested at the same time, the total number of worms and/or the number of mice perfused per week for the worms will not exceed 2,000 worms or the number of mice needed to obtain 2,000 adult worms (Approximately 25 mice.) Approximately 500,000 cercariae shall be required each week. In additional 1 million eggs isolated from tissues of infected mice are to be provided each week. The offeror shall also be responsible for providing approximately 40 hours per week of pathology services. A fixed price contract with a minimum requirement for 1,500 adult worms; 350,000 live cercariae, 750,000 purified eggs, and 0 hours of pathology services per week is contemplated. It is anticipated that this contract will be awarded for one year with six one-year option periods. Any contract awarded will be subject to DHHS regulations regarding the use of animals in research. The animal care must be in accordance with the Guide for the Care and Use of Laboratory Animals, NIH publication No. 86-23, Revised 1996. The Request for Proposals is expected to be issued on or about December 20, 2000. See Numbered Note 1

Record

Loren Data Corp. 20001114/BSOL002.HTM (W-314 SN5064D7)