A -- THE FRAMINGHAM HEART STUDY

Notice Date

December 21, 2000

Contracting Office

Department of Health and Human Services, National Institutes of Health, National Heart, Lung, and Blood Institute, Contracts Operations Branch, 6701 Rockledge Dr RKL2/6100 MSC 7902, Bethesda, MD, 20892-7902

ZIP Code

20892-7902

Solicitation Number

NIH-NHLBI-HC-01-02

Response Due

February 9, 2001

Point of Contact

Cheryl Jennings, Contracting Officer, Phone (301) 435-0345, Fax (301) 480-3430, Email cj19f@nih.gov

E-Mail Address

Cheryl Jennings (cj19f@nih.gov)

Description

The National Heart, Lung, and Blood Institute intends to negotiate on a non-competitive basis with Boston University for a seven year extension of a contract program to continue the Framingham Heart Study. Authority: 41 U.S.C. 253(c)(1) as set forth in FAR 6.302-1. The Framingham Heart Study project began in 1948. Since the late 1960's, this contractor has been involved in recruitment, examination and follow-up of two cohorts totaling 10,333 persons from two separate generations residing in Framingham, Massachusetts in an epidemiology study to identify new risk factors for cardiovascular and lung diseases, to describe the trends and progression of these diseases, and to identify the contribution of genetic and genetic-environmental factors in the development of these diseases. The contract will require full comparability with the on-going study, covering examination and follow-up of both the Framingham Cohort (aged 28-62 at study entry starting in 1948), the Offspring study participants (aged 5-70 at study entry starting in 1971), and identification, examination, and follow-up of the Third Generation participants (an additional 3500 persons). This will entail conduct of a twenty-seventh, twenty-eighth, and twenty-ninth clinic examination of surviving original Framingham participants; an eighth examination of the offspring of original Framingham participants; recruitment and conduct of a baseline examination of the third generation of original Framingham participants; performance of follow-up for morbidity and mortality in all three generations; and performance of comprehensive genetic laboratory and statistical activities, data analysis, and scientific publication efforts utilizing the collected Framingham data. The incumbent contractor has the unique capability to provide these required services to the NHLBI for continuation of this study. Interested respondents must submit written capability statements demonstrating their ability to perform this research effort on the same study participants within 45-days of this announcement. Responses providing insufficient information for evaluation will not be considered. This is not a Request For Proposals. See Note 22.

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Record

Loren Data Corp. 20001226/ASOL008.HTM (D-356 SN5094K3)