66 -- LASER CAPTURE MICRODISSECTION SYSTEM AND SOFTWARE

Notice Date

February 14, 2001

Contracting Office

Department of Health and Human Services, National Institutes of Health, Office of Administration, 6011 Executive Blvd, Rm 538, Rockville, MD, 20892-7663

ZIP Code

20892-7663

Solicitation Number

Reference-Number-BC-0054

Response Due

March 2, 2001

Point of Contact

Sheri Custer, Contracting Officer, Phone 301-402-3065, Fax 301-402-3407, Email custers@od.nih.gov -- Sheri Custer, Contracting Officer, Phone 301-402-3065, Fax 301-402-3407, Email custers@od.nih.gov

E-Mail Address

Sheri Custer (custers@od.nih.gov)

Description

Under authority of U.S.C. 253(c)(1), FAR 6.302-1 the National Institutes of Health (NIH), Bethesda, Maryland intends to negotiate a commercial item type contract with Arcturus Engineering, 1220 Terra Bella Ave., Mountian View, Ca 94043, for a Laser Capture Microdissection (LCM) system and software. LCM technology has been developed by the NIH to provide a rapid and consistently reliable method to procure pure specified cells from specific microscopic regions of tissue sections for subsequent quantitative molecular analysis. The intended procurement will be classified under NAICS 334516, Analytical Laboratory Instrument, Number of Employees 500. This requirement shall include as a complete system, the following salient characteristics, features, and specifications. 1. The system, which includes all necessary software, may be used to study gene and protein expression changes in discrete cells with an identified phenotype. This methodology will allow, for example, the study of gene and protein change induced by various treatments, the cellular phenotype changes characterizing transgenic animals, and changes which may underlie the pathophysiology of mood disorders using postmortem human brain tissue. 2. Shall provide for the ability to procure microscopic tissue samples from human biopsies without extraordinary mounting or slide preparation techniques required. 3. The system shall provide the capability to view the microscopic image of a tissue section. 4. The system shall support, and the user shall be afforded, the capability to select the various cells of interest. 5. The system shall support, and the user shall be afforded, the capability to activate a switch and then obtain only the cells of interest. 6. Shall include recently developed improvements in system design, instrument resolution, and in the software for the capture of images. It is the Government_s belief that these requirements may only be met by Arcturus Engineering, Inc. THIS IS NOT A REQUEST FOR PROPOSAL (RFP), however, concerns that respond to this notice must furnish concise responses directed specifically to the requirements mentioned above. Sources demonstrating the capability to accomplish the above shall supply pertinent information in sufficient detail to demonstrate their ability to perform. Information furnished shall include enough material to perform a proper evaluation. Respondents will not be notified of the evaluation results. Concerns are invited to submit capability statements in an ORIGINAL PLUS TWO (2) copies no later than FIFTEEN (15) business days from the date of this announcement. Written responses shall include complete description of the services to be provided, containing sufficient technical information to permit agency analysis to establish a bona fide capability to meet the stated requirements as listed above. Capability Statements: (a) IF MAILING your capabilities through the U.S. Postal Service use the following address: National Institutes of Health, Office of Logistics and Acquisition Operations, 6011 Executive Blvd., Room 529Q, MSC 7663 ATTN: Sheri Custer, Bethesda, MD 20892. (b) If HAND DELIVERING, OR using a COURIER SERVICE such as: UPS, Federal Express, etc., use the following City, State, and Zip Code: ROCKVILLE, MD 20852. Responses by Facsimile (FAX) will not be accepted. See NOTE: 22 Not withstanding the forty-five (45) day notice for receipt of capability statements all capabilities must be received within FIFTEEN (15) days from publication in the CBD.

Web Link

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Record

Loren Data Corp. 20010216/66SOL014.HTM (D-045 SN50D6M9)