COMMERCE BUSINESS DAILY ISSUE OF MAY 18, 2001 PSA #2854
SOLICITATIONS
A -- NIAID INNER-CITY ASTHMA CONSORTIUM:IMMUNOLOGIC APPROACHES TO REDUCE ASTHMA SEVERITY
- Notice Date
- May 16, 2001
- Contracting Office
- National Institutes of Health, National Institute of Allergy and Infectious Diseases, Contract Management Branch, Room 2230, 6700-B Rockledge Drive, MSC 7612, Bethesda, MD 20892-7612
- ZIP Code
- 20892-7612
- Solicitation Number
- NIH-NIAID-DAIT-02-11
- Response Due
- October 15, 2001
- Point of Contact
- Grace Bruce, Contract Specialist, (301) 496-0195
- Description
- The Division of Allergy, Immunology and Transplantation of the National Institute of Allergy and Infectious Diseases (NIAID), NIH, has a requirement for a Contractor having the capabilities and facilities to establish, coordinate and manage The Inner-City Asthma Consortium. The goals of this Consortium are to develop and carry out a long-range scientific plan to reduce asthma severity and prevent asthma among inner-city children, and to identify the mechanisms involved in the immunopathogenesis of asthma in these populations. Specifically, the Contractor shall: (1) design and conduct clinical trials to evaluate the safety and efficacy of promising immune-based therapies in reducing asthma severity and preventing disease onset in minority children residing in inner cities in the United States; (2) design and conduct research to delineate the underlying mechanisms of such therapies as an integral part of the clinical trials undertaken by the Consortium; (3) design and conduct clinical studies on the immunopathogenesis of asthma onset, progression and severity; and (4) develop and validate surrogate/ biomarkers to measure disease stage, progression and therapeutic effect. The major focus of the clinical trials to be carried out by the Consortium will be on the identification and evaluation of immune-based therapies to reduce asthma severity in inner-city children. To the extent that fundamental knowledge, strategies and investigational agents are available to test approaches to prevent disease onset in children at high risk of developing asthma, such approaches shall be considered and, when appropriate, implemented in clinical trials supported by the Consortium. The major focus of studies on the immunopathogenesis of asthma will be on the pathogenesis of asthma in inner-city children who already have the disease. To the extent that fundamental knowledge and strategies are available to perform studies on the immune mechanisms underlying the onset of asthma in inner-city children at high risk of developing asthma, and that such strategies will provide important information about asthma pathogenesis, such approaches shall be considered and, when appropriate, implemented in clinical studies supported by the Consortium. It is anticipated that one (1) cost reimbursement completion type contract will be awarded for a period of six (6) years, beginning approximately June 1, 2002. RFP NIH-NIAID-DAIT-02-11 will be available electronically on or about May 30, 2001, and may be accessed through the NIAID Contract Management Branch (CMB) Home Page by using the following electronic address and instructions: NIAID CMB Home Page (via the World Wide Web) may be accessed using http://www.niaid.nih.gov/contract. Once at the NIAID/CMB Home Page, click on the "RFPs" link and then click on "RFP NIH-NIAID-DAIT-02-11." Please note that the RFP for this acquisition has been revised to include only the Work Statement, Deliverable and Reporting Requirements, Special Requirements, the Technical Evaluation Criteria, and the Specific RFP Instructions and Provisions. All information required for the submission of an offer will be contained in the electronic RFP package. Following proposal submission and the initial review process, Offerors comprising the competitive range will be requested to provide additional documentation to the Contracting Officer. Responses to this RFP will be due on October 15, 2001. Any responsible Offeror may submit a proposal, which will be considered by the Government. This advertisement does not commit the Government to award a contract. Point of Contact: Grace Bruce, Contracting Officer Electronic mail address: gb15w@nih.gov Telephone: (301) 496-0195 FAX: (301) 402-0972 No collect calls will be accepted.
- Record
- Loren Data Corp. 20010518/ASOL002.HTM (W-136 SN50M2O5)
| A - Research and Development Index
|
Issue Index |
Created on May 16, 2001 by Loren Data Corp. --
info@ld.com
|
|
|
|