A -- DATA COORDINATING CENTER FOR THE OSTEOARTHRITIS INITIATIVE

Notice Date

July 17, 2001

Contracting Office

National Institutes of Health, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Natcher Building, Room 5AS-13A, 45 Center Drive, MSC 6500, Bethesda, Maryland 20892-6500

ZIP Code

20892-6500

Solicitation Number

NIH-NIAMS-02-02

Response Due

November 7, 2001

Point of Contact

Eileen Webster-Cissel, Contracting Officer, 301/594-2543

E-Mail Address

Eileen Webster-Cissel (ew52c@nih.gov)

Description

The description that was originally included with this solicitation notice was not correct. It is replaced by the following: The National Institute of Arthritis and Musculoskeletal and Skin Diseases and the National Institute on Aging, National Institutes of Health, are seeking proposals for a multi-center, longitudinal, prospective, population-based study of knee osteoarthritis (OA) to develop a public domain research resource. The purpose of this resource is to facilitate the scientific evaluation of biomarkers for osteoarthritis (OA) as potential surrogate endpoints for disease onset and progression. This Request for Proposals is to solicit the Data Coordinating Center that will be advising and collaborating with the Clinical Centers in the development and implementation of the study protocol and the enrollment of subjects and the collection of data and biological specimens. The Data Coordinating Center (DCC) will establish protocols, quality assurance methodologies, appropriate computer software for data collection and transmission and databases; will develop recruitment strategies for the Clinical Centers; and will evaluate, read, and interpret radiological materials generated by the Clinical Centers. The DCC will also be expected to develop and implement bioinformatic protocols to handle the massive amounts of data generated and to establish and maintain a web site for these databases. The DCC will be responsible for assimilating, storing, organizing, and coordinating the dissemination of data, x-ray images, and biological specimens from 5000 individuals enrolled in the study. It is intended that minorities and women shall be represented in proportions similar to those found in the U.S. population over the age of 50. It is anticipated that one cost reimbursement contract award will be made for a period of seven years beginning on or about June 1, 2002. The solicitation NIH-NIAMS-02-02 will be available electronically on or about fifteen days from the date of this notice and may be accessed through the Internet at the following address: http://www.nih.gov/niams/grants/rfp/rfplist.htm . Proposals will be due on or about November 7, 2001. Offerors are responsible for downloading their own copy of the solicitation and amendments and for routinely checking the Internet site for any possible solicitation amendments that may be issued by the Government. All responsible sources may submit proposals which will be considered by the Government. The North American Industrial Classification System (NAICS) code for this acquisition is 541710. This advertisement does not commit the Government to award a contract

Web Link

NIH-NIAMS-02-02 (http://www.nih.gov/niams/grants/rfp/rfplist.htm)

Record

Loren Data Corp. 20010719/ASOL002.HTM (W-198 SN50S174)