A -- BIOLOGICAL TESTING FACILITY

Notice Date

August 21, 2001

Contracting Office

National Institute of Child Health and Human Development, Contracts Management Branch, 6100 Bldg., Suite 7A07, 6100- Executive Blvd MSC 7510, Bethesda, MD 20892-7510

ZIP Code

20892-7510

Solicitation Number

RFP NICHD-2001-05

Response Due

October 15, 2001

Point of Contact

Virginia A. DeSeau, Contracting Officer, NICHD, NIH; Telephone: (301) 496-4611; FAX: (301) 402-3676; E-mail: vd9t@nih.gov

E-Mail Address

Click here to contact the Contracting Officer via (vd9t@nih.gov)

Description

The National Institute of Child Health and Human Development (NICHD) is planning to award a contract for a Biological Testing Facility (BTF). This sources sought announcement is presented in an effort to locate all businesses who have the ability to perform the requirements of the BTF. The offeror must have in-house capability of maintaining 2000 rodents, 200 rabbits and 50 non-human primates at any one time in facilities that meet all local, state and federal regulations, and must be currently accredited by the Association for the Assessment and Accreditation of Laboratory Animal Care (AAALAC), conform to the standards outlined in the Responsibilities for the Care and Use of Laboratory Animals (NIH Manual Chapter at: http://www3.od.nih.gov/oma/manualchapters/contracts/6380-2/), the Animal Welfare Act of 1966 and amendments thereto, and have a Radiation Safety Officer in place along with the appropriate licenses for handling radiochemicals and controlled substances. The BTF program is designed to permit rapid evaluation of new compositions of matter, drug formulations delivery systems and devices for anti-fertility and endocrine activity. Such evaluations require the availability of a broad spectrum of in-house biological tests, assays and analytical procedures. These include anti-fertility tests in male and female animals, bioassays, mechanism of action studies, radioimmunoassays of steroid and protein hormones, radio-receptor assays, pharmacokinetic studies and drug safety evaluations. The offeror must have the capabilities and full-time technical staff to undertake these tests along with the capability of housing rodents, rabbits and non-human primates in individual cages when required to do so. The offeror must also provide individuals with experience in conducting studies under Good Laboratory Practice (GLP) guidelines, as needed. The offeror must have the experience, capability and facilities to undertake a wide variety of in vitro transcriptional assays using various cell lines and expression plasmids. The offeror must have the capability of handling proprietary materials, conduct data analyses by standard methods, enter data into Government-furnished data management systems and prepare reports of studies in format and content that are acceptable for submission to the Food and Drug Administration (FDA) in support of a Notice of Claimed Investigational Exemption for a New Drug (IND). The required service is defined as code 541710 under the North American Industry Classification System (NAICS). It is anticipated that one cost-reimbursement option type contract will be awarded as a result of the Request for Proposals (RFP) and the contract is anticipated to have a duration of five years. The RFP represents a re-competition of a project currently being performed by Bioqual, Inc. of Rockville, MD. The Request for Proposals (RFP) will be issued on or about August 21, 2001 and will be available on the NICHD web page at http://www.nichd.nih.gov/oam_cmb . Proposals are due by 4:00 PM EST on October 15, 2001. All responsible sources may submit a proposal for consideration. This advertisement does not commit the Government to award a contract. Proposals should be submitted to Virginia A. DeSeau, Contracting Officer, NICHD, CMB, Executive Building, Suite 7A07; 6100 EXECUTIVE BLVD MSC 7510; BETHESDA MD 20892-7510 (see hand carry address in Section G of the RFP). Telephone, FAX and e-mail addresses are indicated above.

Web Link

Click here to download a copy of the RFP (http://www.nichd.nih.gov/funding/funding-opps_rfp.htm)

Record

Loren Data Corp. 20010823/ASOL009.HTM (W-233 SN50V5H7)