68 -- 68 -- PEPTEDE LIBRARIES

Notice Date

December 27, 2001

Contracting Office

Department of Health and Human Services, National Institutes of Health, National Institute of Allergy & Infectious Diseases/AMOB, 6700-B Rockledge Drive, Bethesda, MD, 20892-7605

ZIP Code

20892-7605

Solicitation Number

RML-RFQ-2008

Response Due

January 10, 2002

Point of Contact

Rebecca Guenthner, Chief Contracting Officer, Phone 301-402-2284, Fax 301-480-3695, Email rguenthner@niaid.nih.gov -- Karin Eddy, Contracting Officer, Phone 301-496-3878, Fax 301-480-3695, Email keddy@niaid.nih.gov

Description

17. This notice is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation, proposals are being requested and a written solicitation will not be issued. This solicitation is being issued as a request for quotations (RML-RFQ-2008). The solicitation documents and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 97-27 (through 06/25/2001). This acquisition will be processed under Simplified Acquisition Procedures (SAP) and is a Small Business Set-Aside. The associated North American Industry Classification system (NAICS) for this procurement is 325998 and the size standard is 500 employees. SCHEDULE: The Rocky Mountain Laboratories, Laboratory of Human Bacterial Pathogenesis (LHBP) has a requirement for peptide libraries consisting of 19-amino acid, biotin-labeled peptides. The LHBP has identified, through genome-scale approaches, a large number of proteins involved in the pathogenesis of infections caused by Group A Streptococcus (GAS). These peptides will be used to identify specific regions of these proteins recognized by the host immune system with the long-term goal of identifying GAS vaccine candidates. We anticipate the need to order an average of approximately 700 peptides per month for a period of 12 months. It is mandatory that the peptide libraries purchased have the following features: 1) The individual peptides must be synthesized using multiple parallel synthesis on polyethylene pins in 8 x 12 96-sample blocks using multi-pin solid phase peptide synthesis technology to minimize costs and turn around time. 2) The resultant peptides must be biotinylated at the aminoterminus and must be synthesized with a 4-residue (S-G-S-G) spacer arm. The synthesis technology must allow the peptides to be cleaved after synthesis on pins, synthesized in 1-5 mmol quantities, and supplied in the final form as lyophilized powder. In addition, Mass Spectral Analysis must be performed on selected peptides as part of the quality control process. 3) The company that will supply the peptide libraries must have the capability to synthesize and supply the peptide libraries within 4-5 weeks of the placement of the order. FOB Point shall be Destination, Hamilton, MT. Inside delivery shall be no more than 30 days after receipt of order (ARO). Delivery location is Rocky Mountain Laboratories, 903 S. 4th Street, Hamilton, MT. The following FAR provisions and clauses apply to this acquisition: 52.212-1 Instructions to Offerors?Commercial; Offerors must include with their offer a completed copy of the provisions at FAR 52.212-3 Offerors Representations and Certifications?Commercial Items. FAR 52.212-2 Evaluation?Commercial Items. The government intends to make an award based on: (1) Capability of the item offered to meet the agency need as stated in the above technical specifications; (2) Price; and (3) Delivery Time FAR 52-212-4 Contract Terms and Conditions?Commercial Items; FAR 52-212-5 Contract Terms and Conditions Required to Implement Statues or Executive Orders?Commercial Items applies to this acquisition. Copies of the above-referenced clauses are available upon request, either by telephone or fax. Offers may be mailed or faxed to the POC indicated above (Fax -- 406-363-9288). Offers must be submitted not later than 4:30 PM (MDST), . January 10, 2002. All responsible sources may submit an offer that will be considered by the National Institute of Allergy & Infectious Diseases. =20

Web Link

Visit this URL for the latest information about this (http://www.eps.gov/spg/HHS/NIH/AMOB/RML-RFQ-2008/listing.html)

Record

Loren Data Corp. 20011231/68SOL001.HTM (D-361 SN516088)